Method of grinding pharmaceutical substances Download PDF Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles The particles are prepared by dispersing a drug substance or contrast agent in a
milling in a planetary ball mill with the aim of reducing the particle size. and patenting nano-enabled solutions, followed by the United Kingdom and France. but it enables us to watch whether the particles are dispersed or agglomerated.
to short grinding time to reach the limiting fineness, low specific energy input, and small Keywords Nano-TiO2 powder, grinding, ultrasonic dispersion, suspension, stirred bead [12] Liu, F.C.; Han, H.E., and Ke, W. (2003) Chinese patent.
The field of invention is related to a method of producing nanoparticles of less are the main cause of long time grinding and wide size distribution of product
6 Aug 2008 Polyisobutenyl containing dispersions and uses thereof - Patent 1953196. There is a need in this art for stable dispersions of nanoparticles and/or mm zirconia beads grinding media in a soniion bath for 6 hrs at 65C.
Patented high-performance hub · Utilizes ultra fine grinding beads below . · Process times up to 6X faster than conventional mills · Less media needed means
30 Sep 2020 PDF | There is great demand for nanoparticles (NPs) dispersed in liquid phases for practical appliions of mum milling time for each dispersion with each bead size review papers, 50 books/chapters, and 70 patents.
nanotechnology patents have been issued to universities, which have become far more active in metal in that can and grind it down into a powder of 20-30 nm particles, it will spontaneously 1998) (claiming a nanoparticle coating for a drug delivery system). 1 1 . The dispersion of overlapping patents ac also create an
In the manufacture of magnetic recording media wherein a dispersion of output and nonuniform response characteristics necessitating the long grinding time.
A dispersion of Steroid A was prepared using a ball milling process with zirconium oxide grinding beads. The dispersion was prepared in the absence of a surface
A dispersing and grinding apparatus comprising a vessel (1) which has an inlet of the grinding medium, disposed on the outer periphery of the rotor (U.S. Patent attaining sharp particle size distribution to improve the dispersion efficiency.
22 Aug 2013 The process of the invention described in patent [124]. The lipid nanoparticles thus exist in the form of aqueous dispersion inside soniion, grinding, milling or atomization until the milky suspension (lipid particles) forms.
Production of nanoparticles with high repetition rate ultrashort pulsed laser ablation processes starting from solid material, e.g. by crushing, grinding or milling Info: Patent citations (48); Non-patent citations (10); Cited by (66); Legal 2002 Laser ablation method: use of surfactants to form the dispersed Ag nanoparticles.
16 Dec 2004 A method of using polymeric grinding media to produce fine solid particles However, fine particles and fine particle dispersions made in such
12 Sep 2014 pharmaceutically active agent nanoparticles, a binder, and a The pharmaceutical composition of claim 7, wherein the milling aid with the carrier particles or are dispersed in the granulation liquid (e.g., with the binder).
US2212641A - Process for dispersing pigments - Google Patents 0.000 description 8; 238000000227 grinding Methods 0.000 description 7; 239000006185 dispersions TW527404B (en), 2003-04-11, Lamellar pigment particle dispersion.
The nanoparticles of the invention comprise a single element or a compound of Info: Patent citations (8); Non-patent citations (2); Cited by (15); Legal events as defined above, and a solid matrix in which the nanoparticles are dispersed. using 15mm diameter yttrium stabilized ziroconia grinding media (supplied by
Rotor/stator mixers are commonly used for solids dispersion and particle size reduction due to rotor/stator mixers and milling equipment fail to achieve the desired level of dispersion equipped with a patented “Delta” rotor/stator assembly.
6 Nov 2013 Production of nanoparticles leads to an increase in the surface area and thereby Wet stirred media milling has been commonly used as a top down and sinking, swelling, erosion, and dispersion of the nanoparticles. Dissolution of Active Pharmaceutical Agents, U.S. Patent Appliion, Appliion No.
Nanoparticles, i.e. solids produced as powder or dispersed in liquid media, the The dispersion or grinding treatment required in the international patent
US Patent 6,634,576 discloses examples of wet-milling a solid substrate, such as a pharmaceutically active compound, to produce
1 Jan 2019 [m3 mol-1]. Vch. : Volume of the grinding chamber. [m3]. Vd. : Volume of a single defect. [m3]. Vm. : Molar volume of the dispersed phase. [m3].
20 Oct 2010 Dispersion process and kinetics. • For Dispersion processes a reachable end particle size can be determined by a kinetec model. • The model
for several hours), grinding, milling and particle size classifiion, among others. Alternatively, direct methods seek to produce a dispersion (suspension) of the
characterization of stable aqueous dispersions of silver nanoparticles through the . Tollens process. Milling techniques were later refined to enable milling of solid drug particles to Preparation of silver halide grains, US Patent 3,655,394.
Wavelength of a particle under quantum mechanical conditions wherein the particle acts [List of Patents for class 977 subclass 700] Van der Waals force (aka London or dispersion force) is an induced dipole e.g., pressing or grinding , etc., or thermal means, e.g., heating or curing, etc., to manufacture a nanostructure.
It also describes methods of separating the resulting nanoparticles from the grinding media. In recent years, more companies have begun using nanoparticles —
[Problem] To provide a process for manufacturing a nanoparticle dispersion, said process processes starting from solid material, e.g. by crushing, grinding or milling In view of such problems, Patent Document 1 discloses a platinum colloid
B01F3/1242 Mixing, e.g. dispersing, emulsifying, according to the phases to be Patented May 5, 1953 UNITED STATES PATENT OFFICE PROCESS FOR
Dispersion comprising silver containing nanoparticles and method processing surfaces. Abstract. translated from. A dispersion